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In 2023, the European Research Council (ERC) is funding 308 researchers in Europe through its “ERC Consolidator grants”, for a total amount of 627 million euros drawn from the Horizon Europe framework program. Supporting the best in exploratory research in three major areas – human and social sciences, physics and engineering and life sciences – these scholarships reward European project leaders who obtained their doctorate 7 to 12 years previously. The “Consolidator” scholarships (up to 2 million euros) are located between the “Starting” scholarships (up to 1.5 million euros and 2 to 7 years after the doctorate) and “Advanced” scholarships (up to to 2.5 million euros and which targets experienced researchers). They are awarded once a year for a period of 5 years to scientists from all countries in the world, but who must carry out their research work in a European or associated country.

SYLVAIN RHEIMS, “ERC CONSOLIDATOR GRANTS” WINNER FOR THE EPIAROUSAL PROJECT ON SEVERE EPILEPTIC SEIZURES

In 2023, the European Research Council (ERC) funds 308 researchers in Europe through its “ERC Consolidator grants”. Professor Sylvain Rheims is the winner with the EPIAROUSAL project which will study severe epileptic seizures.

The EPIAROUSAL (Arousal and respiratory co-dysfunction in drug-resistant epilepsy: from mechanisms to therapy) project will study the interaction between respiratory disorder linked to epilepsy and regulation of wakefulness as well as the relationship between epilepsy, brainstem adenosine and respiratory and arousal co-dysfunction.

It is supported by Sylvain Rheims, University Professor-hospital practitioner (Claude Bernard University Lyon 1, Hospices Civils de Lyon), member of the Lyon Neurosciences Research Center (CRNL, CNRS / Inserm / Claude Bernard University Lyon 1).

Epilepsy is one of the most common neurological diseases. Several of its complications are associated with sleep, including sudden unexpected death (SUDEP), for which no preventive treatment exists. This results from central apnea induced by a nocturnal convulsive attack. Given the interconnections between brain networks that regulate arousal and breathing, some patients may combine a seizure-related respiratory disorder with chronic impairment of arousal regulation. As the adenosine pathway is involved in the regulation of sleep and respiratory control, its alteration could play a key role in these dysfunctions.

EUROPEAN CALL

New Open: NANOTECMEC call for projects

This is a new call for transnational projects aimed at promoting a European health area. This call will take place in two stages, pre-proposals and full proposals, and the process of evaluating full proposals will be associated with a right of responses phase.

Proposals will cover at least one of the following areas of nanomedicine: regenerative medicine, diagnostics, nanotherapy.

The objectives of the call are:

to support translational research projects that combine innovative approaches in the field of nanomedicine;
to encourage and enable transnational collaboration between academic research (public and private partners, i.e. research teams from universities, higher education establishments and public research institutes) and clinical/public health research (research teams of hospitals, health care institutions and other health care organizations) or R&D activities of industrial companies (of all sizes).
The participation of doctors and clinicians is strongly encouraged, as is that of SMEs (small and medium-sized enterprises).

The full text of the appeal is here. More information on the ERA4Health website.

Budget :

Overall NAV: €2M

Max / project: €250K – up to €300K if the coordinator is French.

Calendar :

Deadline for submission of LOIs: January 30, 2024 – 4 p.m.

Complete files: June 13, 2024

The next national call: ANR & ERA-NET NEURON COFUND 2

Multinational and translational research projects on bidirectional interactions between brain and body – ERA-NET NEURON

The ANR is joining forces with the ERA-NET NEURON COFUND 2 to launch an AAP aimed at better understanding the role of bidirectional interactions between the central nervous system and the body in neurological and psychiatric diseases.

This AAP will primarily finance:

– studies with the potential to improve our understanding of the mechanisms underlying brain-body interactions in the context of their implications for brain health and disease, including associated comorbidities,

– research proposals aimed at developing intervention approaches aimed at normalizing dysregulated body-brain communication, provided that they are based on known or hypothetical neural mechanisms.

Research proposals must cover at least one of the following areas:

-Fundamental research on the role of the bidirectional interaction between the body and the brain on the pathogenesis and/or etiology of neurological and psychiatric diseases.

-This may include the development of innovative or shared resources and technologies aimed at normalizing dysregulated body-brain communication.

-Clinical research with a view to developing new prevention, diagnostic, therapeutic strategies and rehabilitation procedures for diseases in which an alteration of body-brain communication constitutes a relevant pathology process.

Excluded from this call:

*Neurodegenerative diseases included in the AAP € Neurodegenerative Disease Research (JPND).

*Projects focusing on neuro-oncology.

*Projects mainly dealing with the functions of peripheral organs (lungs, liver, sensory organs, cardiovascular system, etc.) without focusing on brain-body interaction.

*Projects focusing solely on technological developments without focusing on neurobiological mechanisms.

Budget : Overall €1.8M for 6-7 funded projects.

Calendar : Deadline for submission of pre-proposals: March 8, 2024 2 p.m. on the dedicated platform.

Complete projects: June 28, 2024