Functional Neurosurgery, Spinal and Peripheral Nerves department

The functional neurosurgery service is a pioneering service in the treatment of pathologies of the marrow and nerves. He has thus designed or developed many surgical techniques.

neurologie fonctionnelle-neurophysio


Professor Haegelen is a neurosurgeon in the Functional Neurosurgery department of the P. Wertheimer Neurological Hospital, and professor of anatomy at the Rockefeller Faculty of Medicine (Lyon-Est) at the University of Lyon1.

Currently she is involved as:
– Director of the School of Surgery of the Lyon-Est Faculty of Medicine
– President of the French Society of Neurosurgery (SFNC)
– Responsible for training in functional neurosurgery in France
– Co-director of the Pierre Wertheimer Institute

She is involved, both clinically and scientifically, in the practice and development of epilepsy surgery.

Professor Haegelen used Artificial Intelligence, or Deep Learning, tools, firstly during his research to predict the evolution of patients after deep brain stimulation. This surgery consists of implanting electrodes intracerebral to treat the symptoms of diseases causing abnormal movements. Currently, his main scientific work focuses on the use of Deep Learning tools to better predict the results of epilepsy surgery.

Main areas of research:
Member of the INSERM U1028 team, CNRS UMR 5292, Eduwell team, within the Lyon Neurosciences Research Center.
– Artificial intelligence at the service of epileptic patients: analysis of prognostic factors (EPIL-IA study)
– Evaluation of prognostic factors of response to implanted neurostimulation for chronic pain (PAIN-data study)
– Innovation project for better management of HCL headaches
Links with other national or international teams
– FHU InnovPain: neurosurgical and medical pain teams from the University Hospitals of Nice, Marseille, Clermont-Ferrand, Grenoble and Poitiers
– Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal (Qc), Canada


1. Motor symptom asymmetry predicts cognitive and neuropsychiatric profile following deep brain stimulation of the subthalamic nucleus in Parkinson’s disease: a 5-year longitudinal study.

Voruz P, Haegelen C, Assal F, Drapier S, Drapier D, Sauleau P, Vérin M, Péron JA. Arch Clin Neurophysiol 2023;38(6):904-912

2. Motor symptom asymmetry predicts non-motor outcome and quality of life following STN DBS in Parkinson’s disease.

Voruz P, Pierce J, Ahrweiller K, Haegelen C, Sauleau P, Drapier S, Drapier D, Vérin M, Péron J. Sci Rep 2022;12(1):3007.

3. PassFlow: a multimodal workflow for predicting deep bain stimulation outcomes.

Peralta M, Haegelen C, Jannin P, Baxter JSH. Int J Comput Assist Radiol Surg 2021:16(8):1361-1370.

4. Adapting the listening time for micro-electrode recordings in deep brain stimulation.

Martin T, Gillmore G, Haegelen C, Jannin P, Baxter JSH. Int J Comput Assist Radiol Surg 2021;16(8):1371-1379.

5. Enhancing safety in epilepsy surgery (EASINESS): study protocol for a retropsectiv, multicenter, open registry.

Drexler R, Ben-Haim S, Bien CG, Borger V, Cardinale F, Carpentier A, Cendes F, Chandra S, Clusmann , Colon A, de Curtis M, Delev D, Didato G, Duhrsen L, Farah JO, Guenot M, Haegelen C, et al. Front Neurol 2021 Dec13;12:782666. doi: 10.3389/fneur.2021.782666.

6. Data imputation and compression for Parkinson’s disease clinical questionnaires.

Peralta M, Jannin P, Haegelen C, Baxter JSH. Artif Intell Med 2021;114:102501. doi: 10.1016/j.artmed.2021.102051.

7. Data-driven prediction of the therapeutic window during subthalamic deep brain stimulation surgery.

Baumgarten C, Haegelen C, Zhao Y, Sauleau P, Jannin P. Stereotact Funct Neurosurg 2018;96(3):142-150.

8. Functional atlases to analyze motor and neuropsychological outcomes after medial globus pallidus and subthalamic stimulation.

Haegelen C, Zhao J, Houvenaghel JF, Péron J, Drapier S, Jannin P, Morandi X. PloS One 2018 Jul13;13(7):e0200262. doi: 10.1371/journal.pone.0200262.